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Nitrosative stress leads to the overproduction of RNS, including nitric oxide (NO) which triggers an immune response, and its derivatives: nitrous acid (HNO 2 ), nitrogen dioxide (NO 2 ), and nitric acid (HNO 3 ) (91)

The volume of distribution is approximately 15 L, plasma half-life is approximately 10 minutes, 2 and the average clearance rate is 850 ml/mint/m

In humans, serum levels of ALLO are normally stable during the first 2 years of life (212)

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Cardiometabolic secondary endpoints, including measures such as waist circumference and blood pressure, were reported directionally in favor of the combination arm

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