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C-type lectin receptors), antigen-presenting cells (APCs), including Mo and DCs initiate and maintain Th1 immune responses through antigen presentation and production of inflammatory cytokines such as IL-12, TNF-, IL-6

Here's the connection with glutathione - people with insulin resistance have been shown to have low levels of the antioxidant which suggests a potential link between this antioxidant and metabolic health

Davis, Z

F-AFE significantly reduced -hexosaminidase release (IC 50 = 30.73 g/mL), TNF- (IC 50 = 46.96 g/mL), and PGE2 (IC 50 = 36.27 g/ml) production by IgE-activated RBL-2H3 mast cells in a noncytotoxic and dose-dependent manner [83]

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