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Tingkat TMAO yang tinggi terkait dengan peningkatan risiko aterosklerosis (penyempitan dan pengerasan pembuluh darah arteri akibat penumpukan plak kolesterol)

We found that two key metabolic mediators, acetyl-CoA acetyltransferase 2 (Acat2) and ATP-citrate lyase (Acly), previously shown to control T H 17 cell effector function through glycolytic-epigenetic reprogramming 21 , were downregulated in CD38- compared to IgG-treated 5xFAD mice, 1 month after initiation of the treatment (Fig

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Furthermore, patients with suspected Carneys complex who were PRKAR1A-negative using conventional methods of detection such as polymerase chain reaction were found to have large deletions in this gene