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To investigate what underlines changes in Ca 2+ transients, we assessed levels and phosphorylation state of three major proteins that control the time constant and amplitude of Ca 2+ transient: Na + Ca 2+ exchanger (NCX1), sarco-endoplasmic reticulum Ca 2+ -ATPase (SERCa2), and phospholamban (PLN) (Figure 5C)

Clinical Staging in Psychiatry Making Diagnosis Work for Research and Treatment (Cambridge University Press, 2019)

Muscle tissue burns more calories at rest than fat tissue, so preserving your existing muscle helps maintain metabolic rate even as total body weight decreases

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Dose-Dependent Healing : Effects depend on the amount administered, with higher doses showing faster mucosal repair and stronger anti-inflammatory outcomes in preclinical studies

Both NAD + and NADP + were measurable from the extracts (Supplementary Figure 2u,v)