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Standard protocol: Dose: 1.75 mg subcutaneous injection (approved dose)

In rodents, activation of AMPA receptors by the KET metabolite (2R,6R)-hydroxynorketamine has initially been thought essential to replicate KET antidepressant effects while administration of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-2,3-dione (NBQX), an AMPA receptor antagonist, blocks KET effects (Zanos et al., 2016)

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These are the amounts of vitamin B12 intake per day that are necessary to ensure adequate nutrition in different age groups

Xia H, Scholtes C, Dufour CR, Ouellet C, Ghahremani M, Gigure V