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Common side effects include Nausea (most common, especially during dose increases) Vomiting Diarrhoea Constipation Abdominal pain Fatigue Most side effects are mild to moderate and improve over time

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Across the full screening pipeline, a total of 58 compounds were prioritized for experimental evaluation based on computational performance and commercial availability

By co-activating Y2 and GLP-1 receptors within a single molecule, these dual agonists aim to recapitulate and potentially enhance the natural, complementary actions of the native hormones on appetite suppression, glycemic control, and -cell preservation

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Potential Reduction in Food Cravings and Binge Eating GLP-1 also assists in reducing food cravings and episodes of binge eating