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NICE guidance emphasises that Wegovy should be prescribed alongside a reduced-calorie diet and increased physical activity as part of a comprehensive weight management programme

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NICE guidelines (NG28) support the use of GLP-1 receptor agonists for type 2 diabetes when glycaemic targets are not achieved with other therapies, and for weight management in specific circumstances (TA875 for Wegovy, TA664 for Saxenda)