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Objective biochemical markers like alanine aminotransferase and aspartate aminotransferase, abbreviated ALT and AST, most often improve in clinical trials within eight to twelve weeks

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doi: 10.15252/msb.20199380 79 SteinbrecherTAbelRClarkAFriesnerR

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In addition to the aforementioned withdrawal from GDMT, prolonged QRS interval, presence of LBBB, older age, lower heart rate, and larger LVEDD have been identified as independent predictors of recurrent LVEF deterioration 26

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