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Drives glucose-dependent insulin secretion, suppresses glucagon, slows gastric emptying, and signals satiety via hypothalamic and brainstem pathways

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Clinically, FD presents with mixed hyperlipidemia, characteristic palmar and tuberous xanthomas, and a markedly increased risk of premature and diffuse atherosclerotic cardiovascular disease

Low blood sugar can cause shakiness, jitteriness, and muscle weakness, which some patients describe as a shaky ache throughout the body

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Published work documents protective effects in models of stress-induced gastric ulceration, alcohol-induced gastric injury, NSAID-induced enteropathy, ulcerative colitis, and intestinal anastomosis healing