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They work by suppressing appetite, but side effects such as muscle loss, nausea, and diarrhea have been reported, and it's common to regain the weight after stopping treatment.

For brain function, I specifically like MagPure Brain Boost by Jigsaw Health as it uses magnesium threonate a specific form of magnesium that can cross the blood-brain barrier and target magnesium status in the brain

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In obese individuals, the expression and activity of aromatase in the adipose tissue are enhanced, thereby promoting the synthesis of peripheral estrogen and leading to elevated systemic estrogen levels (66)

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