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LS demonstrates significant protection against Cd-induced hepatointestinal injury, supporting its potential as a therapeutic agent for heavy metal detoxification (131)

To gain additional insights into the mechanism of inhibition, we conducted a series of structural studies

doi: 10.1016/j.redox.2016.05.003 74 LlabaniEHicklinRWLeeHYMotikaSECrawfordLAWeerapanaEet al

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The GSSG is then recycled back to GSH by glutathione reductase (GR) using NADPH that is then converted to NADP +