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The goal is not becoming smaller at any cost
Additionally, the FDA generally prohibits the individual importation of prescription biologics like GLP-1s due to safety and temperature control concerns
Keep weight loss at about 0.5%1% of body weight per week rather than losing too quickly
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Importantly, localized increases in GLP-1, such as that occur in the gut and portal vein, often have a more profound effect than systemic elevations, emphasizing the therapeutic potential of targeting regional activity rather than relying solely on systemic concentrations
Clinicians will also evaluate a patient for medical conditions that might make weight loss more challenging, such as perimenopause or hypothyroidism, which is underactive thyroid
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