retatrutide cardiovascular effects Retatrutide—A Game Changer in Obesity Pharmacotherapy Inotropic effects of retatrutide in

2019;4(12) doi: 10.1172/jci.insight.124819

Repeated acid exposure can lead to permanent damage if not addressed early

In clinical trials for weight management, tirzepatide produced average weight loss of 20-25% of body weight, roughly double what semaglutide achieves at comparable endpoints

However, some cases have shown effects on the thyroid and gastrointestinal tract

Who Is a Candidate for GLP-1 Therapy in Hypothyroidism GLP-1 medications may be considered for hypothyroid patients with persistent weight gain despite TSH optimization, concurrent overweight or obesity (BMI 27 with comorbidities or 30), and absence of contraindications

For questions about GLP-1 medications, speak with a health care provider