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The treatment was 1,000 g of cyanocobalamin (n=54), 1,000 g of cyanocobalamin plus 400 g of folate (n=51), and a placebo (n=57)

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Clinicians should review the patients medication list and use pyridoxine judiciously, adjusting therapy as needed to account for these interactions

Common, usually mild effects include injection-site pain, warmth, or tenderness