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SCD patients have increased thrombotic tendencies due to platelet activation (Nolfi-Donegan et al., 2024)

Preclinical studies in murine models demonstrate that GA-AuNP-mediated photothermal therapy reduces VEGF expression and inhibits angiogenesis, effectively suppressing tumor progression through both thermal and biochemical mechanisms

doi: 10.1172/JCI77588 41 AbdallaSMBiancoAC

Here, we demonstrate that dihexa binds with high affinity to hepatocyte growth factor (HGF) and both dihexa and its parent compound Norleucine 1-AngIV (Nle1- AngIV) induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF- dependent cell scattering

Despite the search was limited to a selection of common oxidative stress polymorphisms, the data collected here are not homogeneous enough to go into a univocal direction