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A 2025 systematic review published in the International Journal of Dermatology reviewed the clinical evidence for glutathione as a skin-lightening agent

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Its antioxidant properties protect cells from oxidative damage, a major contributor to aging-related diseases

In contrast, treated hypertensive patients with a disease duration of five to ten years exhibited a reduced level of lipid peroxidation in the blood [296]

Read it as what has been reported , not as what is known to be safe long-term