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Flavonoids can prevent the formation of damaging radicals, such as hydroxyl radicals formed via the Fenton reaction by the chelation of redox-active metals (copper, iron, manganese) (Simunkova et al

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Practically, that means: Start extremely low sometimes at one-tenth or one-fifth of the usual initial dose

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This article explains how vitamin B6 is used by cells, how it is absorbed and converted, and why genetic variants impact an individuals need for different amounts and different forms of B6

Indian J Med Sci2008;62:167-175 87