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Cellular heterogeneity in both the adult and developing human intestine has been explored extensively using single-cell approaches to study development, homeostasis and disease 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15

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However, LA increased hepatic cholesterol and reduced LDL receptor protein conversion regulatory factors compared with the model group despite reduced mRNA expression of hepatic cholesterol synthesis enzyme (HMG-CoAr) and blood levels of cholesterol and LDL

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