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At follow up, 90% of the shockwave group had satisfactory functional outcome compared to only 50% in the conservative care group

This provides an indirect method of IGF-1 regulation by regulating the level of IGF-2 that is available to bind to the IGF-1R

Thus, Ca 2+ influx through Ca 2+ permeable cation channels is crucial to mediate eryptosis in RBCs, which might be referred to as cation channel-driven eryptosis