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One of the most common and successful therapies for endometriosis pain management is the GnRH agonist, leuprolide acetate ( The use of aromatase inhibitors in the treatment of endometriosis have gained attention based upon the observation that endometriotic lesions express aromatase and are able to synthesize their own estrogen (Yoo et al., 2023)
The GHK-Cu complex is a naturally occurring copper-binding tripeptide found in biological fluids, participating in extracellular matrix remodelling signalling processes
The ischemia generates inflammation which then meets the oxygen in the blood (which can be converted to superoxide) and inflammatory cells (which can create free radicals)
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ScRNA-seq, qRT-PCR, immunofluorescence staining, and statistical analysis revealed that the mitophagy-related genes Becn1 and Lc3 were indeed highly expressed at early-anagen HG compared to the telogen HG (Fig