Therefore, given the emerging evidence for non-anatomic contributors to OSA pathophysiology, as well as the advent of anti-obesity pharmacotherapy [16], the therapeutic landscape for the personalized management of OSA has evolved over the last decade
These findings are supported by a previous study, reporting a reduction in PASI, despite not being statistically significant, together with substantial improvement of BMI and cholesterol levels in an open-label trial of liraglutide in obese PsO patients (59)
doi: 10.1111/nyas.12081 191 de DeusIJOliveiraAFCostaLSAlmeidaJFNascimentoDS
Furthermore, recent studies show the benefits of tirzepatide in people with metabolic dysfunctionassociated steatohepatitis (MASH) [5], in people with heart failure with preserved ejection fraction (HFpEF) and obesity [6], and in people with T2D with established atherosclerotic cardiovascular disease according to a recent press release [7]
Other treatments may include semaglutide, phentermine, Qsymia, Contrave, or Saxenda, depending on your health history, appetite patterns, blood sugar concerns, and how much support you need with hunger and long-term weight management
Comparative Cardiovascular Effectiveness of GLP-1RAs and SGLT2 Inhibitors in Type 2 Diabetes This large-scale, multinational real-world study evaluated the cardiovascular effectiveness of individual glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2is) in over 1.2 million patients with type 2 diabetes on metformin