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However, Thyfault says its unclear if thats a credit to the GLP-1 or a benefit of losing weight overall

Cardiovascular considerations warrant attention in certain populations

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[PubMed: 16904799] (Evaluation of the safety of oral ALA in rats who exhibited no evidence of toxicity except at the highest doses tested [121 mg/kg], which was associated with minor ALT elevations in males and slight changes in liver histology including small droplet fat in periportal regions, but without frank hepatocyte necrosis or inflammation)

10.3945/ajcn.111.027847 Am J Clin Nutr