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Notably, this effect was attributable in part to the preservation of skeletal muscle mass and improved distribution of body fluids

However, in chronic treatments with pegbelfermin, there is a high chance that anti-pegbelfermin and anti-FGF21 antibodies will form, which have been raised concerns about immunogenicity issues

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The five flagship GLP-1 products from these two companiesNovo's Ozempic, Wegovy, and Rybelsus alongside Lilly's Mounjaro and Zepbound have collectively generated over $71 billion in U.S