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Gyurkovics M, Lohinai Z, Gyorfi A, et al

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Second, given that the activation of GSR and TXNRD1 are involved in ROS elimination, if the LCS3-triggered lethality of VRK2-KO PC cells could be attributed to inhibiting the activity of both GSR and TXNRD1, then the level of ROS generated by LCS3 should have been much higher than those produced by the treatment of the TXNRD1 inhibitor auranofin

Vasoactive Intestinal Peptide (VIP) exerts its effects by binding to specific receptors, VPAC1 and VPAC2, which are widely expressed in various tissues

doi:10.7554/eLife.67292 Li X, Zhang B, Hu Y, et al