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This is because when people lose weight, the body's natural inclination is to return to its previous weight a phenomenon called metabolic adaptation

The primary risks include hypoglycaemia (low blood sugar), especially in people with diabetes, and intensified gastrointestinal side effects such as nausea, diarrhoea, and abdominal discomfort

Vidaek N, Nani L, Ravli S, Sopta M, Geri M, Gajski G, Garaj-Vrhovac V, Rubelj I (2018) Telomeres, nutrition, and longevity: can we really navigate our aging

A few6 to consider: Efficacy - not all weight loss patients need to lose much weight

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Frataxin deficiency induces lipid accumulation and affects thermogenesis in brown adipose tissue