[43] Thioridazine represents a critical example, as sertraline can increase thioridazine plasma levels, potentially leading to serious cardiac arrhythmias and QT interval prolongation
The FDA prescribing information includes a boxed warning for risk of thyroid C-cell tumors and contraindication in patients with personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
Availability, eligibility, and dispensing rules can vary, so keep the discussion tied to a valid prescription and clinician oversight
A ) Mean images of brain activation at baseline and week 6 and B ) least squares mean (standard error) change in BOLD fMRI parameters for highly palatable foods vs non-food objects at week 6
95% CI: 1.10, 1.35), while risks of mortality and overall major adverse cardiac events (acute myocardial infarction, cerebral infarction, and/or mortality) were reduced (respectively, HR 0.48 with 95% CI of 0.28, 0.80
"We plan patients appointments ahead of time, ordering multiple tests that will be necessary for the treatment decision-making