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However, the prognosis for MPNST patients remains truly dissatisfactory, with 5-year overall survival (OS) rate of 1566% [1, 4,5,6,7,8,9,10], 5-year event-free survival (EFS) of 2453% [6, 11,12,13,14,15,16,17], and local recurrence (LR) rate of 20% to 85.7% [2, 4, 18,19,20]

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