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The problem prescription GLP-1 medications like Ozempic and Wegovy solve is mimicking GLP-1 so that the medication acts in the body for a much longer period of time

This includes genes governing collagen synthesis, anti-inflammatory cytokines, antioxidant defense, and tissue remodeling pathways

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Weight regain following Retatrutide discontinuation appears consistent with other obesity medications, with 70-85% of lost weight typically returning within 12-18 months without intensive lifestyle intervention

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