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Early- to mid-stage trials in people with obesity (with and without type 2 diabetes) have reported substantial average weight reductions over 48 weeks at higher doses, alongside improvements in measures like waist circumference, blood lipids and liver fat in those with metabolic fatty liver disease

In others, it may not provide the benefits you are hoping for

The effect of metformin therapy on incidence and prognosis in prostate cancer: a systematic review and meta-analysis

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Dual agonists typically target GLP-1R, GIP (glucose-dependent insulinotropic polypeptide) or IGF (insulin-like growth factor) receptors, while triple agonists target GLP-1R, GIPR, and the glucagon receptor (GCGR)

Mounjaro takes this approach further by activating two hormone pathways instead of one