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For rheumatoid arthritis, they are not replacements for your DMARD or biologic but the 2025 research from centers like UCLA suggests they can be a powerful complement: less disease activity, fewer flares, lower inflammation markers, better cholesterol and blood sugar, and reduced cardiovascular risk sometimes even at low doses

The absolute risk for these complications however is extremely uncommon, less than 1 per cent per year of use (Eckert)

The transition should be managed by a clinician

These challenges contribute to many patients stopping GLP-1 therapy

Your healthcare provider will help select between GLP-1 or GLP-1/GIP and a complementary additive, such as B12, L-carnitine, or glycine, based on what aligns best with your wellness goals

Sulfur burp medications include: Simethicone: Helps excess gas pass through your digestive system more quickly