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Moreover, the buildup of fats in muscle cells is associated with lower insulin sensitivity in adults who do not exercise regularly, suggestive of reduced muscle quality

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The Akkermansia species muciniphila has been shown to alter glucose and lipid metabolism as well as intestinal immunity 86 , to strengthen the integrity of the enterocyte monolayer to possibly improve intestinal barrier integrity 87 , and to improve glucose tolerance and reduce visceral adipose tissue inflammation in mice fed an HFD 88