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DNA Damage response and oxidative stress in systemic autoimmunity

It enhances the activity of various enzymes that aid in detoxification, making it an indispensable ally in promoting overall health

This region encompasses a clearly visible phenylalanine (F917) in the cryo-EM structure, but a movement of the downstream region of the -helix, possibly due to a different overall conformation of the entire structure

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Additional preclinical themes include angiogenesis (through endothelial cell migration and tube formation), modulation of inflammatory signalling, and reported effects on cardiac, dermal and neural tissue in animal models

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