Non-heme iron-containing dioxygenases, or LOXs, have been demonstrated to specifically target and oxidize PUFAs, hence promoting lipid peroxidation ultimately triggering ferroptosis (Wang et al., 2021)
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However, owing to its bicyclic backbone structure limitations, an LNA can only spontaneously form A-type hybrid duplexes with target nucleic acid strands
Post-injection, it's generally safe to resume your usual activities