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Firstly, it alters multiple residues in the peptide structure to mimic GIP role at GIPR

Studies utilizing Alzheimers disease models suggest that semaglutide treatment inhibits the activation of microglia and astrocytes, thereby reducing the release of pro-inflammatory mediators (Zhai et al., 2025)

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And the long-term effects, such as improved cardiovascular health and a decreased risk of heart attacks and strokes, are also worth considering

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In colitis, the immune system attacks the cells in the colon lining, causing damage and inflammation