Animal model measurements All animal experiments were carried out according to the University of Ottawa animal care ethics and guidelines (protocol# HS2923)
Metformin administration modulates and restores luteinizing hormone spontaneous episodic secretion and ovarian function in nonobese patients with polycystic ovary syndrome
172 Both groups continued on standard therapy that may have included statins, anti-hypertensives, etc
R&D Systems) in plasma from female [Young ( n = 8), Old Con ( n = 16), and Old mAb ( n = 15)] and male mice [Young ( n = 8), Old Con ( n = 15), and Old mAb ( n = 16)]
The microbiome-mitochondrion connection: common ancestries, common mechanisms, common goals
T ransient nausea, diarrhea, and mild irritation at the injection site have been reported as adverse undesirable effects in preclinical studies