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Mar 2022;36(3):e22173

GIP receptor antagonism eliminates paradoxical growth hormone secretion in some patients with acromegaly

Glutathione S-transferases are a family of enzymes that facilitate glutathiones redox maintenance function by conjugating glutathione onto oxidative substrates, thereby masking their reactivity and enhancing their secretion (Townsend et al,

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The animal data and mechanistic understanding are compelling, but this peptide should be approached with the understanding that human clinical validation is still forthcoming

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