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adults (~32 million people) have taken GLP-1 medications ( [1] ), and roughly 4% of all Americans (~13 million) were on a GLP-1 drug in 2024 ( [2] )

By week 4, appetite suppression was noticeable and consistent with what the clinical literature describes

The real question is whether this space will mature into a legitimate, responsible arm of obesity medicine or be dismissed as a chaotic market of pill mills

PMID:9893707 [6] Falutz J, Allas S, Blot K, et al

however, this requires further investigation

The peptide sequence itself maintains sufficient homology to native GIP (42 amino acids) to activate GIP receptors with high affinity while incorporating specific amino acid substitutions that confer potent GLP-1 receptor agonism