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The type of HT reported before the age of 18 is known as the juvenile variant

The TRIUMPH-4 Phase 3 trial in obesity with knee osteoarthritis (Bays et al., NEJM 2025) reported 28.7% mean weight loss at 68 weeks at the 12 mg dose, plus a 75.8% reduction in WOMAC knee pain scores

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While both medications can be effective for weight loss, research suggests that Zepbound can potentially promote more significant weight loss, helping people lose up to 15%-20% or more of their body weight