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The rodent BDNF gene was initially described by Aid et al (20) and comprises at least eight distinct promoters, initiating the transcription of multiple distinct mRNA transcripts, comprising four 5-exons (IIV) linked to separate promoters, and one 3-exon (V) that contains the entire open reading frame for the BDNF protein

Journal of the American Geriatrics Society , 64 (11), 2263-2269

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Intensity: Moderate to challenging weights that fatigue muscles within 8-12 repetitions

Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate to severe plaque psoriasis over 52 weeks: a phase III, randomized, controlled trial (ESTEEM 2)