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These research-stage amylin-based candidates differ in receptor focus, molecular design, clinical evidence, side-effect profile, and development strategy

Hadley G, Neuhaus AA, Couch Y, Beard DJ, Adriaanse BA, Vekrellis K, DeLuca GC, Papadakis M, Sutherland BA, Buchan AM (2018) The role of the endoplasmic reticulum stress response following cerebral ischemia

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[5], [6], [7] Transcription factors of the FOXO family specifically FOXO1, FOXO3, FOXO4, and FOXO6 are key mediators of insulin and IGF signaling, participating in the regulation of a wide range of cellular processes, including metabolism, cell growth and differentiation, response to oxidative stress, autophagy, senescence, and aging-related processes

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