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Centrally, GLP-1 promotes satiety through the activation of GLP-1 receptors in the hypothalamus and brainstem, which causes a reduction in food intake

While Semaglutide GLP-1 is generally well-tolerated by most patients, it does have potential side effects, including nausea, vomiting, abdominal pain, and diarrhea

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This period is crucial for establishing GLP-1 diet and lifestyle changes , including balanced meals and increased hydration

Participants on the highest dose (7.2mg) lost an average of 20.7% of their body weight 2