2 In addition to lifestyle modifications (diet and exercise), many pharmacologic strategies have been proposed to counter iatrogenic weight gain, including appetite suppressants (eg, pro-dopaminergic agents such as phentermine, stimulants, and amantadine), pro-anorectant anticonvulsants (eg, topiramate or zonisamide), opioid receptor antagonists (eg, olanzapine/samidorphan or naltrexone) and oral hypoglycemics such as metformin
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In the series by Nielsen et al., none of the 32 patients for whom follow-up was available developed a local recurrence, including those with hypercellular lesions
71 In this study, a lactam bridge between Lys i /Glu i +4 was introduced and stabilized a helical conformation at various positions from the N- to C-terminus
7 Bulk hypothalamic RNA sequencing data
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