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The treatment can then be spaced out every two weeks, and eventually once a month as an ongoing source of protection

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The strong effects on spherogenicity in ZH-161 and ZH-305 may involve minor cytotoxic and antiproliferative effects of TGF-2 or EMD1214063 as demonstrated by changes in viability, cell cycle progression and increase of the cyclin-dependent kinase inhibitor p21 under these conditions (Supplementary Fig