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ATP-citrate lyase links cellular metabolism to histone acetylation

Last year, the American Academy of Pediatrics issued new guidelines and recommended the integration of prescription weight-loss medications as part of a comprehensive treatment plan for children with obesity, a condition that the Centers for Disease Control and Prevention says now impacts 1 in 5 kids and teens in the U.S

Thus, inhibiting lipase activity has emerged as a potential therapeutic strategy

Jones et al., 2022

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By the 2010s, athletes adopted it for its tissue-repairing effects, supported by preclinical data