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For the total population scenarios, men were projected to see a greater benefit from both SGLT2is and GLP-1 RAs than women, resulting in lower ICERs for men (the ICERs for SGLT2is were AU$20,361 per QALY for men and AU$28,377 per QALY for women, and those for GLP-1 RAs were AU$96,021 per QALY for men and AU$107,169 per QALY for women)
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4.4.1 GLD-1 pathway The GLD-1 pathway acts redundantly with the GLD-2 and SCF PROM1 pathways to suppress proliferation and/or promote differentiation