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Diabet Med 26:649654 Thondam SK, Cross A, Cuthbertson DJ, Wilding JP, Daousi C (2012) Effects of chronic treatment with metformin on dipeptidyl peptidase-4 activity, glucagon-like peptide 1 and ghrelin in obese patients with type 2 diabetes mellitus

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The safe use of herbs and plant extracts has a long history dating back thousands of years, while modern pharmaceutical drugs - mass-produced, chemically synthesized medications - have only experienced widespread acceptance since the mid 1900s

In that sense, it works as a support system , not a standalone solution