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Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with TRULICITY [see Contraindications (4) and Warnings and Precautions (5.1)]

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Sex Hormones (Estrogen, Progesterone, Testosterone): Changes in sex hormones can also affect weight

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When levels fall, your brain becomes less sensitive to satiety signals, meaning you feel hungry more often and feel full less easily