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HFD recipients pre-treated with antibiotics were orally gavaged with either active or heat-inactivated Adlercreutzia daily for 8 weeks (Figure 5A)

REDEFINE 2 (Phase 3a, NEJM 2025) Davies et al., n=1,206, 68 weeks, T2D + BMI 27

Bacterial cells were washed three times with PBS before infection

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To understand whether a complete TS pathway is operating in Plasmodium , we performed a BLASTP analysis using CBS and CGL sequences of Saccharomyces cerevisiae as the template as this organism possesses a complete TS pathway