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doi: 10.1158/1535-7163.MCT-07-0518

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Most of the DEP's of them were involved in cell death and survival ( n = 103), small molecule biochemistry ( n = 51), nucleic acid metabolism ( n = 29), translation modification ( n = 18) and protein folding ( n = 18)

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In terms of kinase enrichment, pathways related to cell cycle, DNA damage response, cell proliferation and regulation of cytoskeleton organization account for the effects of (M+D)/2 and (M+D+V)/3 compared to the addition of single agents (LIMK1, TESK1, P70S6K, CDK1, CDK2, CAMK4, CAMK2B) ( Figures 7C, D )

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