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For instance, the binding stability of the LRGFGNPPT peptide with the targets AKT serine/threonine kinase 1 (AKT1), angiotensin-converting enzyme (ACE), and renin (REN) was confirmed by 200 ns MD simulation (Gao et al., 2023

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In contrast, alternative materials such as allografts and xenografts for bone defect repair carry potential risks including antigenicity, pathogen transmission, immune rejection and graft resorption (Sivakumar et al., 2022